Effects of Zileuton on Airway Smooth Muscle Remodeling after Repeated Allergen Challenge in Brown Norway Rats
نویسندگان
چکیده
منابع مشابه
Effects of zileuton on airway smooth muscle remodeling after repeated allergen challenge in brown Norway rats.
BACKGROUND Chronic asthma is characterized by airway inflammation and remodeling. OBJECTIVE This study aimed to evaluate the effects of zileuton on bronchial hyperresponsiveness, airway inflammation and airway smooth muscle (ASM) remodeling. METHODS Two experimental groups of brown Norway rats sensitized and repeatedly challenged with aerosolized ovalbumin (OA) were given oral zileuton (OA-...
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ژورنال
عنوان ژورنال: Respiration
سال: 2013
ISSN: 0025-7931,1423-0356
DOI: 10.1159/000353427